Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

African green monkey endogenous virus

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Burkholderia

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Coccidioides

Cronobacter sakazakii

Cryptosporidium

Cynomolgus polyomavirus

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza type A

Klebsiella

Lawsonia intracellularis

Leishmania

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Syphilis

Tetanus

Toxoplasma gondii

Treponema

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

Valley fever

West Nile virus (WNV)

Yaws

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

Zika virus

* * *

Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Simian Varicella Zoster PCR test
primate assay data sheet

Simian varicella-zoster virus (SVV)

Test codes:
S0070 - Ultrasensitive qualitative detection of simian varicella-zoster virus by real time polymerase chain reaction

 

Varicella-zoster virus (VZV), a human herpesvirus, causes varicella or chickenpox, a common infectious disease of childhood. Simian varicella-zoster virus (SVV, Cercopithecine herpesvirus 7) is closely related to varicella-zoster virus and induces a natural varicella-like disease in Old World monkeys. Like human chickenpox, the disease is characterized by fever and vesicular skin rash on the face, torso, and extremities. Following recovery from acute disease, SVV produces a latent infection in neural ganglia and may subsequently reactivate to cause secondary disease and spread to susceptible monkeys. The disease is highly contagious and simian varicella epizootics occur sporadically in facilities housing nonhuman primates. Some epizootics involve high morbidity and mortality, while others are associated with milder disease. Therefore, simian varicella is a useful model to investigate varicella pathogenesis and to evaluate antiviral therapies.

Simian varicella, like human varicella, is believed to be transmitted naturally by inhalation of aerosolized virus-laden droplets, although infection through direct contact with skin lesions is also likely. Diagnosis of varicella disease can be difficult.

Although virus isolation can be used to diagnose SVV infection, a long incubation period is required to obtain results. Furthermore, viral culture is neither sensitive nor specific, and it increases the potential risk of laboratory personnel contacting this virus. SVV detection by PCR is the most rapid, sensitive and specific method for the diagnosis of this infection.

Utilities:

  • Help confirm the disease causing agent
  • Help ensure that animal colonies are free of SVV
  • Early prevention of spread of this virus among a colony
  • Minimize personnel exposure to this virus
  • Safety monitoring of biological products and vaccines that derive from primates

Specimen requirement: Lesion swab or lesion scab, or 0.2 ml whole blood in EDTA (purple top) tube.

Contact Zoologix if advice is needed to determine an appropriate specimen type for a specific diagnostic application. For specimen types not listed here, please contact Zoologix to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time PCR

Normal range: Nondetected

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