Need serology?
Yes, we're still the PCR experts. But Zoologix also performs ELISA antibody tests for...

SRV
Herpes B
SIV
STLV
Measles
Hepatitis A
Hepatitis B
Hepatitis C

* * *

Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Cronobacter sakazakii

Cryptosporidium

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza

Klebsiella

Lawsonia intracellularis

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Toxoplasma gondii

Treponema pallidum

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

West Nile virus (WNV)

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

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Genetic tests for...

A/B/AB blood type in macaques

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Monkey parvovirus PCR test
primate assay data sheet

Monkey parvoviruses: simian, rhesus and pigtailed macaque parvoviruses

Test code:
S0114 - Ultrasensitive qualitative detection of monkey parvoviruses by real time PCR. This assay detects but does not differentiate simian parvovirus, rhesus macaque parvovirus and pig-tailed macaque parvovirus.

 

Simian parvovirus (SPV) was originally isolated during an outbreak of anemia in cynomolgus macaques. Naturally and experimentally infected monkeys have many clinical features similar to those of human B19 infection, such as asymptomatic infection in healthy animals, anemia in immunocompromised monkeys, and fetal hydrops in pregnant macaques.

Soon after the discovery of SPV, two similar outbreaks of anemia in rhesus and pig-tailed macaques were reported and led to isolation of two distinct but similar simian parvoviruses (pig-tailed macaque and rhesus parvovirus).

Like human B19 virus, SPV contains a short piece of single stranded DNA. The genomic organization and the protein-coding strategy of SPV are very similar to those of human parvovirus B19. Because of these close similarities, SPV can replicate in vitro in both human and macaque bone marrow mononuclear cells and is cytotoxic to erythroid progenitor cells. Thus SPV may infect human bone marrow mononuclear cells in vitro and in vivo and should be considered a potential zoonosis.

Molecular detection by PCR of parvovirus carrier status or infection in monkeys has much higher sensitivity and specificity than serology, according to a recent study on B19 diagnosis (Gallinella et al., 2003).

Utilities:

  • Help confirm the disease causing agent
  • Help ensure that animal colonies are free of parvoviruses
  • Early prevention of spread of parvoviruses among a colony
  • Minimize unnecessary occupational exposure to these viruses
  • Safety monitoring of biological products and vaccines that derive from monkeys

Reference:
Gallinella, G., Zuffie, E., Gentilomi, G., Manaresi, E., Venturoli, S., Bovincini, F., Cricca, M., Zerbini, M. and Musiani, M. (2003) Relevance of B19 markers in serum samples for a diagnosis of parvovirus B19-correlated diseases. J Med. Virol. 71:135-139.

Specimen requirement: 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube, or 0.2 ml cell culture.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time polymerase chain reaction.

Normal range: Nondetected

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