Zoologix performs primate infectious disease tests by PCR for...


African green monkey endogenous virus


B virus


Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi



Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis



Cronobacter sakazakii


Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian


E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species


Epstein-Barr virus


Gibbon ape leukemia


Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster



Lawsonia intracellularis



Lyme disease







Neisseria gonorhoeae

Neisseria meningitidis



Plasmodium species

Reovirus screen

Rhesus rhadinovirus



Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes



Toxoplasma gondii

Treponema pallidum


Trypanosoma cruzi



Valley fever

West Nile virus (WNV)

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

Zika virus

* * *

Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements

STLV 1 and 2 PCR test
primate assay data sheet

Simian T-cell lymphotropic/leukemia virus (STLV) types 1 and 2 by PCR

Test codes:
S0014 - Qualitative detection of STLV type 1 by polymerase chain reaction
S0015 - Qualitative detection of STLV type 2 by polymerase chain reaction
P0005 - Qualitative screen for primate T-cell leukemia/lymphotropic viruses (STLV and HTLV) by real time polymerase chain reaction

The human T-cell leukemia virus (HTLV) is divided into two serologically and genetically distinct types (HTLV-1 and HTLV-2). Both types have a simian relative: HTLV-1 is related to simian T-cell leukemia virus type 1 (STLV-1) and HTLV-2 is related to STLV-2. STLV-1 infects a wide range of wild nonhuman primates (NHPs). Natural infection with STLV-1 can be found among macaques, guenons, mangabeys, baboons, and apes in Asia and Africa. However, STLV-2 has only been identified in captive bonobos (Pan paniscus). The natural occurrence of STLV-2 is still unknown. HTLVs and STLVs are collectively called primate T-cell leukemia virus (PTLV).

For reasons of occupational safety and animal health, as well as to improve the quality of nonhuman primates (NHPs) used in biomedical research, the establishment and maintenance of specific retrovirus-free breeding colonies of NHPs such as macaques are now high priorities. Viruses which have a widespread occurrence and a strong potential for cross-species transmission such as STLV top the priority list. Although virus isolation can be used to diagnose STLV virus infection, it requires a long period of time to obtain results. Furthermore, viral culture is neither sensitive nor specific, and increases the potential risk of laboratory workers contacting this virus. Serological detection of STLV infection is also not very reliable, sensitive or specific. False negative and false positive results occur frequently. A recent study has shown that experimental infection of macaques with STLV-I can be serologically silent for more than 43 months.

STLV detection by PCR is the most rapid, sensitive and specific method for the diagnosis of this infection. The method can also differentiate the virus from other closely related polyomaviruses.


  • Help confirm the disease causing agent
  • Help ensure that animal colonies are free of STLV
  • Early prevention of spread of this virus among a colony
  • Minimize personnel exposure to this virus
  • Safety monitoring of biological products and vaccines that derive from primates

Specimen requirement: 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube.

Contact Zoologix if advice is needed to determine an appropriate specimen type for a specific diagnostic application. For specimen types not listed here, please contact Zoologix to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

and S0015 - Qualitative PCR
P0005 - Qualitative real time PCR

Normal range: Nondetected

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