Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

African green monkey endogenous virus

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Burkholderia

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Coccidioides

Cronobacter sakazakii

Cryptosporidium

Cynomolgus polyomavirus

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza type A

Klebsiella

Lawsonia intracellularis

Leishmania

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Syphilis

Tetanus

Toxoplasma gondii

Treponema

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

Valley fever

West Nile virus (WNV)

Yaws

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

Zika virus

* * *

Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Neisseria gonorrhoeae PCR test for primates
primate assay data sheet

Neisseria gonorrhoeae

Test codes:

B0012 - Ultrasensitive qualitative detection of Neisseria gonorrhoeae by real time polymerase chain reaction.

P0003 - Chlamydia trachomatis and Neisseria gonorhoeae screen by real time polymerase chain reaction. This screen detects but does not differentiate N. gonorhoeae and C. trachomatis.

Neisseria gonorrhoeae are gram-negative diplococcus bacteria. Although humans are the only natural host for these bacteria, other species have been infected experimentally, including guinea pigs, rabbits, mice, hamsters, rats, rhesus monkeys, chimpanzees, and baboons.

In humans, infection with these bacteria causes gonorrhea, a sexually transmitted disease of worldwide significance. The highest attack rate in both men and women occurs between 15 and 29 years of age. Host-related factors such as the number of sexual partners, contraceptive practices, sexual preference, and population mobility contribute to the incidence of gonorrhea. N. gonorrhoeae can grow and multiply easily in warm, moist areas, including the cervix, uterus, and fallopian tubes in women, and in the urethra in women and men. The bacteria can also grow in the mouth, throat, eyes, and anus.

These bacteria adhere to columnar epithelial cells, penetrate them, then multiply on the basement membrane. Adherence is facilitated through pili and opa proteins. Infection with these bacteria can result in urethritis, cervicitis, salpingitis, pelvic inflammatory disease, proctitis, conjunctivitis and pharyngitis. Transmission occurs through direct contact.

Detection of N. gonorrhoeae by PCR is highly sensitivity and specific (Luijt et al., 2005).

Utilities:

  • Help confirm the disease causing agent
  • Shorten the time required to confirm a clinical diagnosis of Neisseria gonorrhoeae  infection.
  • Help ensure that colonies are free of N. gonorrhoeae
  • Early prevention of spread of N. gonorrhoeae
  • Minimize personnel exposure to N. gonorrhoeae
  • Safety monitoring of biological products

References:
Luijt, D.S., Bos, P.A.J., van Zwet, A.A., van Voorst Vader, P.C. and Schirm, J. (2005) Comparison of COBAS AMPLICOR Neisseria gonorrhoeae PCR, including Confirmation with N. gonorrhoeae-specific 16S rRNA PCR, with traditional culture.  J. Clin. Microbiol. 43:1445-1447

Specimen requirements: 0.2 ml urine, or urogenital swab, or vaginal swab, or eye swab, or 0.2 ml bacterial culture.

Contact Zoologix if advice is needed to determine an appropriate specimen type for a specific diagnostic application. For specimen types not listed here, please contact Zoologix to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time PCR

Normal range: Nondetected

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