Zoologix performs primate infectious disease tests by PCR for...


African green monkey endogenous virus


B virus


Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi



Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis



Cronobacter sakazakii


Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian


E. coli O157:H7

E. coli panel

Encephalitis, Japanese

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Entamoeba species


Epstein-Barr virus


Gibbon ape leukemia


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Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

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Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

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Human Varicella-Zoster



Lawsonia intracellularis



Lyme disease







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Plasmodium species

Reovirus screen

Rhesus rhadinovirus



Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes



Toxoplasma gondii

Treponema pallidum


Trypanosoma cruzi



Valley fever

West Nile virus (WNV)

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

Zika virus

* * *

Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements

Herpes papio PCR tests
primate assay data sheet

Herpesvirus papio 1 and 2 (HVP-1 and HVP-2)

Test codes:

S0052 - Qualitative detection of herpesvirus papio 1 (HVP-1) by polymerase chain reaction
S0027 - Qualitative detection of herpesvirus papio 2 (HVP-2) by polymerase chain reaction


Infection of baboons with herpesvirus papio 2 (HVP-2) produces a disease that is similar to human infection with herpes simplex viruses (HSV). HVP-2 infection is associated with oral and genital lesions that resemble HSV infections of humans. Male baboons develop erythema of the penis with papules or pustules that develop into small ulcerative lesions. Female baboons have been observed with ulcerative lesions on the vulvar tissues. Juvenile animals were found to have primarily oral lesions. Acquisition of genital infection is primarily associated with the onset of sexual activity in baboons. Furthermore, one study provided evidence that the virus could spontaneously reactivate from latency, a pattern consistent with HSV infection of humans.

Serological analysis has determined that over 90% of wild-caught baboons were found to have anti-HVP-2 titers, confirming that baboons are a natural host for HVP-2. However, it is not clear what percentage of them are active carriers of this virus.

Although virus isolation can be used to diagnose HVP-2 virus infection and determine carrier status, a long incubation period is required to obtain results. Viral culture also increases the potential risk of laboratory personnel contacting this virus. Furthermore, viral culture is not as sensitive or specific as PCR-based techniques. Serological testing for HVP-2 antigens is difficult because of the close antigenic relation between surface antigens among the alphaherpesviruses. HVP-2 detection by PCR is the most rapid, sensitive and specific method for the diagnosis of this infection and confirmation of the carrier status of the animal.


  • Help confirm the disease causing agent
  • Help ensure that animal colonies are free of HVP-1 and HVP-2
  • Early prevention of spread of these viruses among a colony
  • Minimize personnel exposure to these viruses
  • Safety monitoring of biological products and vaccines that derive from primates

Specimen requirement: 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube.

Contact Zoologix if advice is needed to determine an appropriate specimen type for a specific diagnostic application. For specimen types not listed here, please contact Zoologix to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative PCR

Normal range: Nondetected

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