NEW - Neuro symptoms getting on your nerves? Try our canine neurological panel - 6 neurological pathogens from 1 CSF sample; or our feline neurological panel - 5 neurological pathogens from 1 CSF sample.

Oh baby! Try our canine breeding PCR panel - 3 canine sexually transmitted diseases tested from swabs or semen samples.

Respiratory symptoms got you breathless? Try our canine respiratory PCR panel - we test for 6 canine respiratory pathogens from throat, nasal and eye swabs.

...or maybe you need our feline respiratory PCR panel -- 6 feline respiratory pathogens from throat, nasal and eye swabs.

Diarrhea got you on the run? Try our canine diarrhea PCR panel -- 8 major diarrheagenic agents from 1 fecal specimen...
...OR our 9-pathogen feline diarrhea PCR panel.

Not feeling sanguine about bloodborne pathogens in cats? Try our feline bloodborne PCR panel -- 4 major bloodborne pathogens from 1 blood sample.

Ticks bugging you? Try our tickborne disease PCR panel -- 7 major tickborne pathogens from 1 blood sample.

Just plain sick and tired? Try our canine anemia PCR panel or our feline anemia PCR panel -- detect and differentiate multiple anemia pathogens from 1 blood sample.

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Zoologix performs canine and feline PCR tests for...

Anaplasma phagocytophilum

Anaplasma platys

Aspergillus species

Aspergillus fumigatus

Babesia

Bartonella

Baylisascaris procyonis

Bordetella bronchiseptica

Borrelia burgdorferi

Brucella

Campylobacter

Canine adenovirus type 1

Canine adenovirus type 2

Canine enteric coronavirus (CCV1)

Canine distemper

Canine herpesvirus

Canine papillomavirus

Canine parainfluenza virus

Canine parvovirus

Canine respiratory coronavirus (CCV2)

Chagas disease

Chikungunya virus

Chlamydophila psittaci

Clostridium species

Coccidia

Cryptococcus

Cryptosporidium

Cytauxzoon felis

E. coli

Ehrlichia

Fading kitten syndrome

Feline calicivirus

Feline distemper

Feline enteric coronavirus

Feline foamy virus

Feline herpesvirus type 1

Feline immunodeficiency virus

Feline infectious anemia

Feline infectious peritonitis

Feline leukemia

Feline panleukopenia

Feline papillomavirus

Feline pneunomitis

Feline rhinotracheitis virus

Feline sarcoma virus

Feline syncytial virus

Francisella tularensis

Giardia

Group G strep

Haemobartonella canis

Haemobartonella felis

Helicobacter

Influenza

Lawsonia intracellularis

Leishmania

Leptospira

Lyme disease

MRSA (Methicillin-resistant Staph aureus)

Mycoplasma canis

Mycoplasma felis

Mycoplasma haemocanis

Mycoplasma haemofelis

Neospora caninum

Pasteurella multocida

Pneumocystis carinii

Rabies

Reovirus screen

Rickettsia screen

Salmonella

Sarcocystis neurona

Streptococcus, Group G

Streptococcus pneumoniae

Streptococcus pyogenes

Streptococcus zooepidemicus

Toxoplasma gondii

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tularemia

West Nile virus

Yersinia pestis

Yersinia pseudotuberculosis


Canine adenovirus 1 PCR test

dog and cat assay data sheet

Canine adenovirus type 1 (CAV-1)

Test code:
S0119 - Ultrasensitive qualitative detection of canine adenovirus type 1 by real time polymerase chain reaction

 

Infectious canine hepatitis (ICH) is caused by canine adenovirus type-1 (CAV-1), a pathogen closely related to but distinct from canine adenovirus type-2 (CAV-2). CAV-1 is found worldwide and is spread by body fluids including nasal discharge and urine. The primary mode of transmission is by direct contact with infected animals. Contaminated runs, cages, dishes, hands, boots, etc can also serve as a source of transmission.

Infected dogs may have sore throat, coughing, and occasionally pneumonia. When the virus enters the bloodstream, it can affect the eyes, liver, and kidneys. As the liver and kidneys fail, there may be seizures, increased thirst, vomiting, and/or diarrhea. Dogs with healthy immune systems can fight the virus by producing antibodies. However, the virus can remain in the kidneys and be shed in the urine for up to nine months, posing a threat to other dogs.

Unvaccinated dogs of all ages are at risk, but the disease is especially prevalent in dogs less than one year of age. Death can result as soon as two hours after the initial signs. Death can be so sudden it may appear as if the patient was poisoned.

Serological detection of CAV-1 is not reliable because of the possibility of cross-reacting with closely related virus, such as CAV-2 (Gore et al., 2005). Molecular detection of CAV-1 nucleic acid by PCR offers a rapid, sensitive and specific alternative for diagnosing the disease.

Utilities:

  • Help confirm the disease causing agent
  • Help ensure that animal groups and populations are free of canine adenovirus type 1
  • Early prevention of spread of CAV-1 among a population
  • Minimize human exposure to this virus
  • Safety monitoring of biological products and vaccines that derive from susceptible animals

References:
Gore, T.C., Lakshmanan, N., Duncan, K.L., Coyne, M.J., Lum, M.A., and Sterner, F.J. (2005) Three-year duration of immunity in dogs following vaccination against canine adenovirus type-1, canine parvovirus, and canine distemper virus. Vet. Ther. 6:5-14.

Specimen requirement: Nasal swab, conjunctival swab, rectal swab or corneal scraping, or 0.2 ml feces or urine, or 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube, or 0.2 ml fresh, frozen or fixed tissue.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time PCR

Normal range: Nondetected

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