Screening your mice? Try our Mouse Essentials PCR Panel. All the most important mouse colony screening tests, all by expert real time PCR...

...or how about our new Mouse PCR Minipanel - PCR tests for only the most common mouse pathogens - for economical colony screening...

...and don't forget our Mouse Fecal PCR Panel - includes 9 important fecal pathogens.

And... just for rabbits: our new Rabbit Fecal PCR Panel tests for 3 common causes of GI problems in rabbits.

For wild rodent infestations, remediation and environmental monitoring, use our Rodent Infestation PCR Panel

* * *

Zoologix also performs rodent and rabbit PCR tests for...

Aspiculuris tetraptera


BXV-1 virus



Clostridium piliforme


E. coli (enteroinvasive)



Encephalitozoon cuniculi


Francisella tularensis

Fur mites



Human adenoviruses

Klebsiella pneumoniae

K virus

Lactate dehydrogenase-elevating virus


Lymphocytic choriomeningitis virus (LCMV)


Mouse adenoviruses

Mouse cytomegaloviruses

Mouse hepatitis virus (MHV)

Mouse kidney parvovirus (MKV or MKPV)

Mouse minute virus (MMV)

Mouse norovirus (MNV)

Mouse parvovirus (MPV)

Mouse polyoma virus (POLY)

Mousepox virus (aka ectromelia virus, EV or ECTRO)

Mouse rotavirus

Mycoplasma pulmonis

Mycoplasma screen



Pneumocystis carinii

Pneumonia virus of mice (PVM)

Rabbit coronavirus

Rabbit fibroma virus

Rabbit hemorrhagic disease virus

Rat bite fever

Rat coronavirus

Reovirus screen

Reovirus type 3 (REO3)



Sendai virus (SEND)

Seoul virus


Sialodacryoadenitis virus (SDAV)

Streptobacillus moniliformis

Streptococcus pneumoniae

Syphacia muris

Syphacia obvelata

Theiler's murine encephalomyelitis virus (TMEV)

Tickborne encephalitis virus

Treponema cuniculi/ paraluiscuniculi


Tyzzer's disease

Whitewater Arroyo virus

Yersinia enterocolitica

Yersinia pestis

Yersinia pseudotuberculosis

Mouse adenovirus PCR test

rodent and rabbit assay data sheet

Mouse adenovirus 1 and 2 (MAD-1 and MAD-2)

Test codes:
- Ultrasensitive qualitative detection of mouse adenovirus 1 (MAD-1) by real time PCR
- Ultrasensitive qualitative detection of mouse adenovirus 2 (MAD-2) by real time PCR

S0146 and S0147 are included on P0029 - Mouse Essentials Panel

Mouse adenoviruses are DNA viruses; there are two strains, group 1 (MAD-1) and group 2 (MAD-2). These viruses infect both mice and rats.

Infection with these viruses does not cause clinical disease in adult rodents, and there are no pathologic lesions associated with infections of MAD-1 in adult mice. However, MAD-1 infection can produce a lethal disease in newborn or suckling mice characterized by infectious virus and viral lesions in multiple organs. Viral inclusions in intestinal mucosa are associated with MAD-2 infections.

Infection of mice or rats with adenoviruses can alter their normal immune response and thereby skew experimental data. For example, infection with MAD-1 can produce extensive persistent lesions in the kidneys of adult mice and render them more susceptible to experimental Escherichia coli-induced pyelonephritis. Mouse adenovirus infection has also been shown to accelerate experimental scrapie infection in mice. Although mouse adenoviral infection is usually subclinical in immunocompetent mice, wasting may result in nude mice.

Serological detection may not be useful because many mice and rats may have prior exposure to these viruses. Hemagglutination methodology is also not suitable for mouse adenovirus detection because these viruses simply will not hemagglutinate. Molecular detection of adenoviruses is rapid, specific and sensitive to detect the presence of the viruses.


  • Help confirm the disease causing agent
  • Shorten the time required to confirm a clinical diagnosis of mouse adenoviruses
  • Help ensure that vivariums are free of mouse adenoviruses
  • Early prevention of spread of mouse adenoviruses among a vivarium
  • Minimize personnel exposure to these viruses
  • Safety monitoring of biological products that derive from mice

Implications of infectious agents on results of animal experiments. Report of the Working Group on Hygiene of the Gesellschaft für Versuchstierkunde--Society for Laboratory Animal Science (GV-SOLAS). Lab. Animal. 1999; 33 Suppl 1:S39-87.

Specimen requirements: 0.2 ml whole blood in EDTA (purple top) tube; or 0.2 ml tissue, or 0.2 ml cell culture.

Contact Zoologix if advice is needed to determine an appropriate specimen type for a specific diagnostic application. For specimen types not listed here, please contact Zoologix to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time polymerase chain reaction

Normal range: Nondetected

©2003-2023 Zoologix, Inc. • Email Zoologix • Phone (818) 717-8880