Klebsiella pneumoniae

Test code: B0060 - Qualitative ultrasensitive detection of Klebsiella pneumoniae bacteria by real time polymerase chain reaction.  This assay detects and differentiates a genomic target and two virulence factors, magA and rmpA.

 Studies have shown that while magA presents exclusively in the K1 capsular serotype, rmpA can be detected in either K1 or K2 capsular serotypes and also in approximately two-thirds of non-K1/K2 capsular serotypes.

Utilities:

• Confirm the disease causing agent
• Shorten the time required to confirm a clinical diagnosis of Klebsiella pneumoniae infection
• Ensure animal groups and populations are free of Klebsiella pneumoniae
• Differentiate virulent from non-virulent Klebsiella pneumoniae strains
• Identify magA and rmpA virulence factors in Klebsiella pneumoniae strains
• Early prevention of spread of these bacteria among a population
• Minimize human exposure to these bacteria
• Safety monitoring of biological products and vaccines that derive from susceptible animals

Specimen requirement:

Preferred specimens - rectal swab, 0.5 ml feces, or oral swab.

Less preferred specimen - 0.5 ml whole blood in EDTA (purple top) or ACD (yellow top) tube.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time PCR

Normal range: Nondetected