primate genetic test data sheet
Fetal sex determination for
macaques by PCR
Nonhuman primates have reproductive characteristics, placental
structures and development events very similar to those of
humans. Thus, primates are often used in studies of fetal
development, or drug-drug interactions during fetal development.
Non-invasive fetal sex determination is necessary for some
biomedical studies because of differences during male and female
fetal development. The male phenotype is controlled by the
sex-determining region Y gene (SRY gene). This gene is on the Y
chromosome, which is not present in females. Therefore,
detection of this gene target in fetal DNA circulating in
maternal blood is a non-invasive indicator of a male fetus
(Mitsunaga et al., 2010).
Determine macaque fetal sex from a maternal blood sample
Mitsunaga, F., Ueiwa, M., Kamanaka, Y., Morimoto, M. and
Nakamura, S. (2010)
Fetal sex determination of macaque monkeys by a nested PCR using
Exp. Anim. 59:255-260.
0.2 ml fresh or frozen EDTA maternal whole blood, or
ml frozen maternal plasma or serum
Contact Zoologix if advice is needed to determine an appropriate specimen type for a specific diagnostic application. For specimen types not listed here, please contact Zoologix to confirm specimen acceptability and shipping instructions.
For all specimen types, if there will be a delay in shipping, or
during very warm weather, refrigerate specimens until shipped
and ship with a cold pack unless more stringent shipping
requirements are specified. Frozen specimens should be shipped
so as to remain frozen in transit. See
shipping instructions for
Turnaround time: 3 business days