Need serology?
Yes, we're still the PCR experts. But Zoologix also performs ELISA antibody tests for...

SRV
Herpes B
SIV
STLV
Measles
Hepatitis A
Hepatitis B
Hepatitis C

* * *

Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Cronobacter sakazakii

Cryptosporidium

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza

Klebsiella

Lawsonia intracellularis

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Toxoplasma gondii

Treponema pallidum

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

West Nile virus (WNV)

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

* * *

Genetic tests for...

A/B/AB blood type in macaques

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Marburg PCR test for primates

primate assay data sheet

Marburg virus

Test code:
S0150 - Ultrasensitive qualitative detection of Marburg virus by reverse transcription coupled real time polymerase chain reaction

 

Marburg virus is a single-stranded, negative sense RNA virus belonging to the Marburgvirus genus, which contains one species, Lake Victoria marburgvirus. The virus causes the disease Marburg Hemorrhagic Fever (MHF), or Marburg Virus Disease. Marburg virus was first discovered in Central and East Africa, and was found to infect both human and nonhuman primates. The Marburg virus belongs to Filoviridae, the same taxonomic family as Ebola virus.

The virus can be transmitted through blood, saliva, excrement, vomit and other bodily fluids. Early symptoms of viral infection are often non-specific and usually include fever, headache and muscle ache. Maculopapular rash is often present on the trunk after five days of infection. This progresses into acute symptoms which include jaundice, pancreatitis, weight loss, delirium and neuropsychiatric symptoms, hemorrhaging, hypovolemic shock and multi-organ failure. Currently, there is no specific treatment for infected patients and supportive care is the only option. The fatality rate is from 23% to over 90% (1, 2).

Marburg virus is a biosafety class IV agent. Caretakers of animals that are suspected to be infected should take appropriate precautions.

Serological detection of Marburg virus can be slow because antibody response may take some time to develop. However, PCR is a rapid, highly sensitive and highly specific technique for detection of this virus.

Utilities:

  • Help confirm the disease causing agent
  • Help ensure that animal colonies are free of Marburg virus
  • Early prevention of spread of the virus among a colony
  • Minimize personnel exposure to the virus
  • Safety monitoring of biological products and vaccines that derive from primates

References:
1.       World Health Organization (2005) Marburg virus disease, Angola. Wkly Epidemiol Rec 80: 115–117.

2.       Centers for Disease Control and Prevention (2005) Outbreak of Marburg virus hemorrhagic fever-Angola, October 1, 2004–March 29. Morb Mortal Wkly Rep 54: 308–309.

Specimen requirements: 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube, or 0.2 ml plasma or serum.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative reverse transcription coupled real time PCR

Normal range: Nondetected

2003-2014 Zoologix, Inc. • Email Zoologix • Phone (818) 717-8880